WormLab Imaging System

WormLab® Imaging System

The revolutionary system that analyzes worm behavior and delivers light and tapping stimuli

WormLab software is known for providing an amazing amount of data about worm locomotion in an intuitive user interface. Now, the WormLab Imaging System works in conjunction with WormLab software so you can correlate C. elegans locomotory behavior with the delivery of tapping or light stimuli.

The WormLab Imaging System is a complete,  scalable solution for automated  imaging and quantitative analysis of  the behavior of C. elegans and other nematodes.  We worked closely with world leading  C. elegans researchers to develop a unique worm tracking system that is intuitive and easy to use so you spend less time on set-up and maintenance and more time focused on your research.

Customer Reviews

"We really appreciate the help from all the staff at MBF Bioscience. Expert support combined with their excellent product WormLab are essential for our research on C. elegans behavior in my lab."
Jihong Bai, Ph.D.
Fred Hutch
"WormLab provides far superior data than the other conventional programs used for worms. Our work with WormLab has been extremely rewarding because it puts us on the frontier of the behavior studies of C.elegans and allows us to carry out differentiated experiments, with software that is easy to use and needs only simple equipment."
Félix Soares, PhD
University Professor and Researcher, Universidade Federal de Santa Maria, Brazil
"MBF provides excellent technical support and helps you to find the best technical tools for your research challenges on morphometry."
Wilma Van De Berg, Ph.D.
VU University Medical Center - Neuroscience Campus Amsterdam
"Our experience with the MBF equipment and especially the MBF people has been outstanding. I cannot speak any higher about their professionalism and attention for our needs."
Bogdan A. Stoica, M.D.
University of Maryland

High-resolution worm imaging 

  • Specialized optical system ensures maximum resolution, contrast and sharpness – ideal for machine vision
  • Captures a variety of experimental paradigms, inlcuding:

    •  Simultaneous tracking of multiple worms                     

    •  Swimming & Thrashing worms

  • Whole plate tracking capability increases assay efficiency

Automated optogenetics & mechanosensation

  • Full automation to increase efficiency and repeatability of assays
  • Easily correlate behavior with programmable light or tapping stimuli


  • Easy data acquisition & analysis with WormLab’s intuitive software interface
  • Scalable plug and play design expands with your application requirements 

Enclosed design

  • Prevents ambient light from influencing the behavior of your worms
  • Improved environment for delivering stimuli
  • Fast glide adjustment mount for quick and repeatable change of the working distance for mulitple zoom levels (8mm to 50mm FOV) without the need for any tools. This type of flexibility is not found in conventional compound microscopes or dissecting scopes

Camera with macrolens for high-resolution images

  • Fast high-resolution USB 3.0
  • Nikon 60mm macro lens – Close Range Correction System ensures high resolution throughout the adjustment range of the camera stand


Light stimulus delivery

  • High output LED lights illuminate the worms
  • Light patterns controlled with WormLab software

Tapping stimulus delivery

  • Variable force/patterns controlled with WormLab


Macro Illuminator - generates even illumination across a large field of view to create a high contrast image

  • The illumination system creates solid, high-contrast images of the normally transparent worms
  • Light path starts with a precisely adjustable, white or red light LED source and diffuser module
  • Housing has integral cooling fan to account for thermal management of the LED itself and avoids coupling heat to the specimen
  • Diffuser element mitigates hot spots within the 50mm FOV creating a flat field background
  • Light then passes through a series of optical elements evenly illuminating the specimen with collimated light producing a very high contrast











Professional Technical Support

When you call us you will speak with a person - not an automated system. Talk to us about your hardware, software, or experimental design questions. Our team includes Ph.D. neuroscientists and experts in microscopy, stereology, neuron tracing, and image processing; ready to help you over the phone or online.


System Requirements for Microsoft Windows

  • For Microsoft Windows PCs, we recommend Windows 8 or 10 64-bit with 4GB RAM and a dual core or better Intel processors (i3,i5,i7).
  • WormLab can also run on Windows XP 32 bit or Windows 8 or 10 32-bit. The 64-bit version of Windows 8 offers a significant performance improvement over the 32 bit version. WormLab software takes under 100MB of disk space, but adequate hard disk space for video files is needed (250GB recommended) and an internet connection for activation.


System Requirements for Apple OSX

Mac OSX 10.9 or later is required, running on a Mac with Intel processors. For camera support, your Mac will require a Firewire (IEEE1394) port. Requirements include 4GB RAM, adequate hard disk space for video files (250GB recommended) and an internet connection for activation.


We can also custom develop for you

MBF is proud to help bioscience leaders and experts push the next wave of innovation and discovery to benefit humanity. Given this, it’s possible you’re looking for customized technology for your needs. If that is the case, click here to get in touch with us directly. We’d be happy and honored to see if we can create something together that will move all of us forward.

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